eCureMe logo
  eCureMe home eCureMe log In Sign Up!
eCureMe Life : Your Healthy Living. Click Here!
Welcome, medical contents search April 26, 2013
       eCureMe Life
       Medical Supplies
       Calorie Count
       Physician Search
       Message Board
      E-mail Doctor
      E-mail Veterinarian
      Health-O-Matic Meter
      Calorie Count
      Natural Medicine
      Vitamins & Minerals
      Alternative Living
      My Health Chart
      Diseases & Treatments
      Atlas of Diseases
      Sexually Transmitted
Generic Viagra
      Drug Information
      Illegal Drugs
      Lab & Diagnostic Tests
      Internal Medicine
      Women’s Health
      Eye Disorders
      Skin Disorders
      Mental Health
      Resource Links
      Physician Directory
      Dentist Directory
      Hospital Directory

Charcot-Marie-Tooth Disease

more about Charcot-Marie-Tooth Disease

Hereditary sensorimotor neuropathies

  • Charcot-Marie-Tooth disease is a type of peripheral Neuropathy, characterized by a slowly progressive weakness and wasting of the muscles in the upper and lower extremities.

  • Charcot-Marie-Tooth disease causes destruction of the peripheral nerves.
    There are two main types: The onset of type I occurs in early adulthood.
    In type II, inheritance is autosomal recessive (the onset is in early childhood). In both types, the nerves of both lower limbs are commonly affected and symptoms of the hand may appear in later stage of disease.
    1. Slowly progressive symmetric muscle weakness and wasting of feet and legs, characterized by foot drop, foot deformity (high arch and toe flexion deformity), gait difficulty and "stork leg" appearance due to the wasting of both lower leg muscles
    2. Loss of sensation and numbness in the toes and lower legs
    3. Muscle weakness and numbness of the hands in the later stages

  • The specific cause is unknown.
  • Charcot-Marie-Tooth disease can be inherited with both autosomal dominant or recessive patterns.
  • Autosomal dominant inheritance is the most common pattern.
  • There are also sporadic cases without a family history of Charcot-Marie-Tooth disease.

  • Nerve conduction test and Electromyography
  • Muscle biopsy
  • Nerve biopsy confirms the diagnosis

  • There is no known cure

  • Physical therapy to minimize the loss of muscle power and maintain functional independence
  • Proper shoes or orthopaedic surgery for foot deformities
  • Proper footcare to prevent Foot Ulcers that results from sensory loss and foot deformity

  • The expected life span is normal, but the slow and progressive muscle weakness causes eventual disability, including gait difficulty, foot deformity and deformities of spine curvature (scoliosis).

more about Charcot-Marie-Tooth Disease

If you want your friend to read or know about this article, Click here

medical contents search

Home   |   About Us   |   Contact Us   |   Employment Ad   |   Help

Terms and Conditions under which this service is provided to you. Read our Privacy Policy.
Copyright © 2002 - 2003 eCureMe, Inc All right reserved.