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Gluten enteropathy or
celiac disease
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- Celiac Disease is
characterized by damage to part of the small intestine,
interfering with the body's natural ability to absorb food
and nutrients properly. The actual cause is not known, but
there appears to be a genetic component. In addition, an
autoimmune phenomenon (the body's immune system mistakenly
attacks the intestines) probably is a major factor.
- Though the actual cause is unknown,
the elimination of gluten from the diet often resolves the
symptoms, and causes the small intestine to heal in nearly
all cases. Gluten is the protein portion of wheat, rye,
barley, and oats. Wheat flour, the major component in bread
and most baked goods, must be
eliminated.
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- Abdominal Bloating
- Flatulence ("Gas")
- Greasy stools
- Weight loss
- Weakness
- Constant hunger
- Easy Bruising
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- Genetic predisposition
- Probably autoimmune (see
above)
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- Loss of muscle mass
- Loss of body fat
- Itching blisters
- Complete blood count
- Serum iron, folate, vitamin B12, Calcium, Alkaline phosphatase, albumin, beta-carotene
- Prothrombin time
- Stool test for fat in stool
- D-xylose test-not commonly done any more, checked for
malabsorption
- IgG and IgA anti-gliadin antibodies
- IgA endomysial antibody
- Intestinal biopsy (can be done with endoscopy-passing
scope through
esophagus)
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- Remove all gluten-containing
products from the diet -- wheat, rye, barley, and oat
products.
- Carefully read ingredients on the
package of all baked goods and processed foods, as they
often contain gluten in one form or another. Gluten is not
only the primary ingredient in breads, crackers, and
pastries, but it is often added to many manufactured foods.
- Rice, corn, potato, and soybean
flours are safe to use.
- Expect improvement in about two
weeks.
- Rare individuals who fail diet
restrictions may need corticosteroids or Cyclosporine (both
treat autoimmune
diseases).
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- 10% of individuals with celiac sprue develop intestinal Lymphoma (a form of cancer). If symptoms recur after elimination of gluten from the diet, then intestinal Lymphoma should be
suspected.
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