Natural Medicine : DUPUYTREN'S CONTRACTURE
What is Dupuytren's Contracture?
Slowly a finger, or fingers, is drawn down toward the palm or wrist. This action is
caused by the connective tissue in the palms and fingers becoming short and thick, too short
and thick to allow free movement of the fingers. Baron Guillaume Dupuytren, a French surgeon,
described the surgical treatment for the disease now bearing his name in 1832, and reported it in
Lancet in 1834. The cause of it is not understood well, but some things have been learned in
Surgery has been considered the only treatment, and there are controversies over the type of
procedure which should be used. Should it be an extensive excision or limited excision of the
connective tissue in the palm and fingers? And when in the progress of the disease is it best to
operate, early or late? And there is controversy over whether the wound should be left open or
closed after the surgery.
In all methods of treatment currently used in standard medicine, we find a disappointingly high rate
of recurrence after what appears to be successful operations. We believe alternative methods should
be applied as soon as the first symptom appears. Every attempt should be made to arrest the progress
of the disease before it becomes disabling. However, if natural remedies fail to halt the disease, we
believe delaying surgery as long as possible to be the more desirable course
Inheritance is the most important factor; Whites, especially those of Celtic origin, have the highest
incidence, and it runs in families. It is uncommon in pigmented races, and males are at least twice as
often affected as females, in some reports as high as 7 to 1. The peak incidence is between the fifth
and the seventh decades of life.
High blood fats (cholesterol and triglycerides) have been associated with Dupuytren's disease.1 Ideal
blood lipid levels are 100 plus the person's age for cholesterol, and the same as the age for triglycerides.
Several associated diseases have been observed, including epilepsy, diabetes, alcohol abuse, heart
disease, and pulmonary disease. Note that each of these diseases is usually treated with powerful drugs,
which may unite their metabolic disturbances with the metabolic disturbance of the disease to cause growth
of the connective tissue in the palms and fingers.
One study showed alcoholics have a higher rate of this disease than others-28 per cent as compared to
8 per cent.2 Several studies have indicated an association between some kind of immune disorder and
Dupuytren's contracture in susceptible persons.3
Type II diabetes (adult onset) with absent or reduced insulin receptors on cells of the palmar connective
tissue, with a disturbance of the smallest blood vessels and nerves, (micro angiopathy and neuropathy),
as well as cigarette smoking, and other factors such as barbiturate use, promote the development of
connective tissue disorders.4,5,6
Ideal Blood Lipids
Cholesterol = 100 plus your age
Triglycerides = Your age
It was once thought occupational trauma and Peyronie's disease, a male genital tract disease, were factors,
but now are recognized not to be factors. Yet, the right hand is more often affected, the ring finger (forth)
being most often involved, followed by the small, middle, and index fingers.
Physical forces, such as electrical fields, seem to be indicated by some research in causing Dupuytren's
contracture. Electrical fields have had bad press in many areas, also including cancer.7
The younger the patient, the more rapidly it progresses. The commonest first sign is a fleshy nodule in the
palm, usually located at the base of the ring or small finger in the crease where the finger joins the hand.
The nodule may be painful or itch, and may reach one half inch in diameter. It is followed by puckering of
the skin of the palm over the involved tendon.
Several treatments have been tried and failed to alter the course of the disease, including vitamin E, steroid
injections, radiation therapy, ultrasound, and splinting. It has been said that successful conservative treatment
is possible only at the very beginning of the disease.8 Nevertheless, at whatever stage you are, we recommend
the following home remedies be applied very carefully:
The most favorable diet is a totally vegetarian diet-no meat, milk, eggs, or cheese. Damage from xanthine
oxidase, which is found in homogenized milk, was discovered in the palmar connective tissue of patients
with Dupuytren's contracture. Xanthine oxidase has also been found in the joints of both normal and
rheumatoid joints, suggesting these joints may be the target of damage by free radicals promoted by
Use no free fats-margarine, mayonnaise, fried foods, cooking fats, salad oils, or nut butters. Free fats
cause tissue proliferation in certain diseases (cancer and skin lesions), and could be a factor. Free
radicals are compounds with unpaired electrons, making them chemically active. Since they are not
harnessed in any way, they can shoot around and cause damage. They are developed from fats, and
play a part in inflammation, autoimmune diseases, and possibly help cause Dupuytren's contracture.10
Be regular in your schedule-especially with mealtimes, bedtimes, etc.
Do physical exercise to tolerance, at least 6 days a week. This should be done with religious consistency.
Finger and wrist exercises have helped in trials using also heat and massage.11 Get a sponge ball from
a toy department and try to make your thumb meet each finger, one by one, through the sponge ball using
a pinching motion. Begin with five repetitions with each finger, and build up to twenty. Then squeeze the
ball as firmly as possible, and while holding the squeeze tightly, slowly bend the wrist up and down as if
Soak hands and wrists in hot water four times a day for 20 minutes each time, for two months, and after the
hands become warm the fingers should be manipulated and stretched by firm massage and pulling or
pushing. The use of ultra sound with the heat has proved beneficial in many cases.12 Some cases
have been effectively treated and corrected with ultrasound. Severely contracted hands will sometimes
A long period of fasting, 3 to 5 days, at the beginning of the treatment may be helpful. This should be
followed by a diet sufficient to keep the blood sugar between 70 and 85, the blood pressure under 120/80,
and the blood cholesterol and triglycerides in the ideal range.
If hypertension is also present, the patient should be given a very strict routine of blood pressure control.
(See our Blood Pressure book.)
While free fats and oils of all kinds should be removed from the diet, nuts, seeds, avocadoes, and olives,
may be used as desired. All free sugars should also be removed from the diet such as sugar, honey,
syrup, molasses, etc. Fruits may be eaten freely, however
1. Journal of Bone and Joint Surgery 74B:923-927, November, 1992
2. Journal of Hand Surgery 17:71-4;1992
3. Journal of Hand Surgery 16:267-71; 1991
4. Diabetes Research and Clinical Practice 11:121-5; 1991
5. Archives of Internnal Medicine 149:911-4; 1989
6. Journal of Hand Surgery 11:463-4; 1986
7. Annales de Surgery Chirugie de la Main et du Membre Superieur 11(5):355-61;1992
8. Seminars in Arthritis and Rheumatism 3(2):155;1973
9. British Medical Journal 296:292-293;1988
10. Journal of Bone and Joint Surgery 70-B:689;November 1988
11. Journal of American Geriatrics Society 16:531; 1968
12. Heat Therapy and Ultrasonics 208:125;1972
13. Physiotherapy 66:55; 1980