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- Guthrie test: < 2 mg/day/L
- Fluorometry method
- Normal newborn: 1.2-3.4 mg/ dl
- Premature newborn: 2-7.5 mg/ dl
- Adult: 0.8-1.8 mg/ dl
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- To detect PKU and other causes of hyperphenylalaninemia
- To monitor patients who have PKU and are being maintained on a phenylalanine-restricted diet; Elevated blood level of phenylalanine will cause central nervous system damage and mental retardation.
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- PKU
- Severe burns
- Hyperphenylalaninemia
- Liver disease
- Sepsis
- Galactosemia
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- Little to no ingestion of milk
- Insufficient quantity of blood
- Antibiotics
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