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Cutaneous T cell lymphoma
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Abnormal |
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- This is a type of Lymphoma (cancer of the lymph cells) that involves the skin. In most cases, it is very slow growing (over many years). Risk factors include exposure to metals, solvents, petrol chemicals, and HTLV-1 infection.
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- Red scaling patches
- Skin ulcers
- Late in the disease the spleen or liver, or both may enlarge.
- Area affected is usually at least 2 inches
- Lymph gland swelling occurs later in the disease
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- Skin biopsy
- Sezary cells -- abnormal cells may be present in the blood
- HTLV-1 blood serology
- Electron microscopy
- Chest X-Ray
- Abdominal CAT scan
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- Mechlorethamine ointment (nitrogen mustard)
- Topical corticosteroids
- PUVA (ultraviolet light therapy) treatment
- REPUVA is retinoids added to PUVA treatment
- Radiation
- Chemotherapy (Methotrexate) for advanced disease
- Interferon and Interleukin-2 are two of the newer forms of therapy.
- Electron beam therapy
- Combination therapy for advance disease
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