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Korsakoff's Psychosis

more about Korsakoff's Psychosis

Korsakoff's syndrome

  • This is a syndrome caused by a deficiency of thiamin (also called vitamin B1) and abuse of alcohol.  It is characterized by amnesia.  Patients may also confabulate, ramble in their speech, and make up stories as they go along (about imaginary events).
  • Wernicke's Encephalopathy is also associated with Thiamin Deficiency and alcohol abuse.  However, in this syndrome, the patient is confused, walks unsteadily, and has double vision.

  • Intravenous thiamin
  • Unfortunately, only 25% of patients with this syndrome fully recover after thiamin treatment.  50% have a partial recovery, while 25% show no improvement at all. (Note: Wernicke's Encephalopathy generally resolves itself rapidly with thiamin treatment).
  • Of course, alcohol abuse should be treated.

more about Korsakoff's Psychosis

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