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Huntington's Chorea

more about Huntington's Chorea


Huntington's disease


  • This is a form of Dementia that begins between the ages of 30-50.  It tends to progress to death over the next 15-20 years.
  • Huntington's Chorea is a genetic disease associated with characteristic jerky involuntary spasms, called chorea.

  • Initial:
    1. Abnormal movements
    2. Intellectual changes
    3. Behavioral changes
    4. Irritability
    5. Antisocial behavior
    6. Moodiness
    7. Psychiatric disorders
  • Later:
    1. Dementia (senility)
    2. Chorea -- repetitively purposeless movements of the extremities
    3. Rigidity may occur

  • Genetic (autosomal dominant)

  • Made by symptoms and history
  • CT scan -- brain atrophy and atrophy of the caudate nucleus

  • Currently there is no cure
  • Supportive care for the individuals to help them function in their environment
  • Genetic counseling for family members
  • Supportive care for the family
  • Haldol or phenothiazines may help with psychiatric symptoms
  • Reserpine may help movement problems

  • The patient with this disorder is at risk of injuring himself and others, if psychiatric symptoms are severe.  Depression is common.  People with this disease are at risk of suicide.

  • Syndenham's chorea




more about Huntington's Chorea


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