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Enzymes and Isoenzymes, Cardiac
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- Creatine phosphokinase (CPK) or creatine kinase (CK)
- Adult male: 5-35 µg/ml, 20-170 IU/L
< 90 U/L, 5-55 mU/ml
- Adult female: 5-25 µg/ml, 10-135 IU/L
< 80 U/L, 5-35 mU/ml
- Male child: 0-70 IU/L
- Female child: 0-50 IU/L
- Newborn: 65-580 IU/L, 10-200 U/L
- CPK-MM (skeletal muscles): 90-97% of total CPK
- CPK-MB (heart): 0-6% of total CPK
- CPK-BB (brain): Trace or 0% of
total CPK
- Aspartate aminotransferase (AST) or
serum glutamic oxaloacetic transaminase
- Adult: 8-20 U/L
- Older adult
- Male: 11-26 U/L
- Female: 10-20 U/L
- Child (< 5 years): 19-28 U/L
- Infant: 15-60 U/L
- Newborn: 16-72 U/L
- Lactic acid dehydrogenase (LDH)
60-120U/ml
- LDH isoenzymes: 70-200 IU/L
- LDH1: Heart, red blood cells, 14-26%
- LDH2: Reticuloendothelial cells and kidney, 29-39%
- LDH3: Lungs, lymphatics, spleen, and others, 20-26%
- LDH4: Kidney, placenta, liver, 8-16%
- LDH5: Kidney, liver, and skeletal muscle, 6-16%
- Serum alphahydroxybutyrate dehydrogenase:
50-250 U/L
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- To determine myocardial tissue
damage
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- Cardioversion
- Drugs (alcohol, aspirin,
halothane, lithium succinylcholine)
- Muscle Trauma
- Recent vigorous exercise,
surgery
- Drugs (acetaminophen,
antituberculous agents, aspirin, chlorpromazine,
erythromycin)
- Muscle Trauma
- Strenuous
fasting
- Pregnancy
- Prosthetic heart
valves
- Recent surgery
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