- Acne Vulgaris is a skin disorder characterized by cysts, open and closed comedones (plugged lesions containing a "cottage-cheese" like material), pus pockets, and raised red swellings.
- Often occurs in puberty, though may
occur in the 20s or 30s.
- May actually occur in neonates
- Open and closed comedones
- Pus pockets
- Raised, red areas of skin
- Pustular lesions (infected scabs)
- Most commonly on face, back, and
- Scarring may occur over time
- Pain, soreness, and itching may
- May improve in summer
- May worsen before menses
- Males have a more severe form of
acne, and a later onset than females.
- The true cause is often unknown.
Androgens (hormones) tend to trigger in those predisposed.
- Plugging of hair follicles by a protein known as keratin causes the formation of so-called whiteheads and blackheads, which form when the plugged sebaceous glands within the hair follicles continue to secret sebum (an oily secretion). Sebum and skin cells cannot exit, thus accumulating in mass, causing the follicle to swell. If the swelling continues, it may rupture, allowing the surface bacteria (normally found on the skin) to enter and cause local infections (e.g., zits or Pimples). The zits may
then enlarge and form cysts.
- Irritation by inflammatory fatty
acids within the plugged follicles, and an overgrowth of the
bacteria Proprionibacterium together contribute to the
process of acne formation.
- Irritating creams and oils
- Topical steroid creams
- Corticosteroid medication taken
- Adolescence, male sex, certain drugs (e.g., Dilantin, Lithium,
birth control pills, steroids), humid/hot weather,
supplements (e.g., DHEA), and constant skin friction (e.g.,
use of motorcycle helmets, telephones) are some of the
common risk factors.
- Avoid manipulating or infecting acne
lesions by touching with hands.
- Diet does not seem to play a role
unless the patient notices a certain food that makes his
- Comedo extraction done with a comedo
- Benzoyl peroxide available over the
counter in many forms such as gels, washes, etc. Stronger
is not better (2.5% is just as effective as 10% solution,
but less irritating).
- Topical antibiotics such as
Clindamycin (Cleocin), Erythromycin Gel.
- Antibiotics by mouth such as
Tetracycline, Erythromycin, and Minocycline
- Treninoin (Retin A) cream or gel
- Isoretinoin (Accutane) -- this is a
very strong medicine that must be followed carefully by
your doctor. This drug causes significant birth defects,
so pregnant women must avoid it.
- Intra-lesion injection: deep acne
lesions and cysts are injected with a corticosteroid
- Note: all medications usually take
six weeks or more to realize
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