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IgA Nephropathy

more about IgA Nephropathy


Berger's disease, focal glomerulonephritis



  • This is a kidney disorder in which IgA antibodies deposit in the internal kidney structures and cause inflammation.
  • It is more common in boys than girls.

  • Family history of IgA nephropathy or Henoch-Schonlein purpura

  • Bloody urine
  • Dark, brown, or rust-colored urine
  • High blood pressure
  • Edema

  • Based on symptoms and physical examination
  • Urine tests show blood, red cell casts, protein and fat in the urine.
  • Kidney biopsy shows deposits of IgA antibodies.
  • Immunoelectrophoresis of urine shows antibodies to IgA.

  • Antihypertensive medications
  • Diuretics
  • Low-to-moderate protein diet in some cases
  • Immunosuppressive therapy for progressive IgA nephropathy

  • Renal failure
  • High blood pressure

  • It progresses in 30% of patients.
  • Poor prognosis is associated with:
    1. High blood pressure 
    2. Diminished kidney function
    3. Histologic evidence of diffuse glomerulonephritis with crescents and scarring




more about IgA Nephropathy


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