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Welcome, medical contents search April 25, 2013
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Ureteropelvic Junction Obstruction

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UPJ obstruction

  • Ureteropelvic junction obstruction (UPJ) is a blockage of the tube (ureter) from the kidney to the bladder, just below the kidney, that can cause the kidney to swell beyond its normal size.  It can be present at birth due to abnormalities in the ureter, such as kinks caused by scar formation or abnormal tissue.  UPJ can also be associated with other birth defects of the kidney, bladder, and intestinal tract.  UPJ is the most common obstruction of the urinary tract in childhood.

  • Mothers carrying infants with this condition can have smaller or larger abdomens than expected.
  • Newborn children can have an abdominal mass with occasional abdominal, flank, or back pain.
  • Frequent bladder and Kidney Infections
  • Occasionally blood in the urine
  • Older children may have elevated blood pressure

  • Prior to birth, the enlarged kidneys may be detected on an ultrasound study.
  • Various means are available to study kidney function, and these will need to be repeated as the child matures, to access kidney function.
  • Fewer than 15% of infants with UPJ require surgical correction.

  • Daily antibiotics can be given to prevent bladder and Kidney Infections.
  • Fetal surgery is very risky, but can been performed if the condition is life-threatening.
  • Surgery to remove the abnormal area of obstruction can also be performed.
  • Rarely, the affected kidney may need to be removed when it has been severely damaged, has multiple cysts, or is severely infected.

  • None, as it is a congenital condition.

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