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Post-Inflammatory Hypopigmentation
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- After the skin has been subjected to an irritant, the body mounts an "inflammatory response" with movement of white blood cells and other cells into the area, to repair any damaged tissue.
- When irritation and inflammation has subsided, pigment may have been lost from the skin if the pigment-containing cells (melanocytes) are damaged or destroyed.
- This can leave an area of skin with less pigment than normal (i.e., hypopigmentation).
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- There are no symptoms, but there is a physical sign -- hypopigmented or de-pigmented areas of skin are seen.
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- Any condition that provokes an inflammatory response
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- Compatible (fits the criteria) history of inflammation of the skin
- Visual inspection of the skin shows hypopigmented or de-pigmented areas.
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- Acne
- Eczema
- Psoriasis
- Seborrheic Dermatitis
- Varicella
- Certain medications may produce hypopigmentation as a side effect.
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- Medication, administered by different routes
- Topical treatments to improve the cosmetic appearance
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- Sun sensitivity to UV light, which may be marked sensitivity
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