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Central nervous system agent
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Mild or moderate pain; fever; various inflammatory conditions such as Rheumatic Fever and myocardial infarction.
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Minor aches or fever: 325 mg to 650 mg every 4 hours if needed, or 500 mg every 3 hours, or 1000 mg every 6 hours. Myocardial infarction: Coated aspirin (325 mg) once or twice daily. Rheumatic arthritis patients: 3.2 g to 6 g daily in divided doses. Children: 10-15 mg/kg/dose every 4 hours if needed (up to 60-80 mg/kg/dose).
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Category D
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Hives, rashes Angioedema, nausea or vomiting, GI bleeding, thirst, and dimness of vision.
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Pregnancy Risk Categories defined:
A: Studies in pregnant women failed to show a risk to the fetus in the first
trimester - with no evidence of risk in the later trimesters.
B: Animals studies indicate no adverse effect to the fetus, but there are no adequate,
clinical studies in pregnant women.
C: Animal studies have shown an adverse effect on the fetus, but there are no adequate,
clinical studies in humans. Despite potential risks, the drug may be useful in pregnant
women.
D: There is evidence of risk to the human fetus, but the potential benefits of use in
pregnant women may be acceptable, despite potential risks.
X: Studies in animals or humans show fetal abnormalities, or adverse reaction reports
indicate evidence of fetal risk. Warning: the risks involved clearly outweigh any
potential benefit from using the drug in pregnant women, regardless of trimester.
NR: Not rated (i.e., no information available at this time as to the potential
risks or benefits).
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